Shrinkage estimation of gene interaction networks in single-cell RNA sequencing data Full Text

This prior information is then leveraged by optimizing the prototype loss on each set of labeled prototypes. To simulate such a scenario, we integrated the HLCA, but this time using both a coarse and a fine annotation (Supplementary Fig. 4a–c). Additionally, for one dataset in the reference (Krasnow2020), we kept only the coarse annotation. We …

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